Orajel® Severe Toothache Pain Relief Cream delivers the highest concentration of pain medicine available without prescription for instant relief of your most painful toothaches. The Severe Formula also features menthol, which cools and soothes the affected area. The thick cream is long-lasting and easy to apply so you get relief that lasts, where you need it most. Orajel Severe Toothache Cream goes right to the source of your pain for instant, targeted relief. Don’t trust your toothache pain to anything else.